Antimicrobial Susceptibility Testing
We specialize in providing comprehensive testing solutions to assess the effectiveness of antimicrobial agents against microbial pathogens. Our laboratory offers a wide range of traditional antimicrobial susceptibility testing methods, including broth microdilution, disk diffusion, and agar dilution. These well-established techniques allow us to determine the susceptibility profile of microorganisms and provide crucial information for guiding treatment decisions.   In addition to the standard methods, we offer a cutting-edge approach known as the hollow-fibre infection model. This dynamic model provides a sophisticated in vitro simulation of infection scenarios, mimicking the complex interactions between microbes and antimicrobial agents within the human body. By utilizing the hollow-fibre infection model, we can assess the activity of antimicrobial agents under conditions that more closely resemble the in vivo environment. This advanced technique provides valuable insights into drug efficacy, resistance development, and optimal dosing regimens. Our experienced team of scientists combines expertise in microbiology, pharmacology, and data analysis to ensure accurate and reliable results. We adhere to stringent quality control measures, following internationally recognized guidelines and standards. You can trust in our commitment to delivering precise and actionable susceptibility data. Preclinical HFIM pharmacokenetic/ pharmacodynamic experiments for: dose ranging, synergy testing at clinical concentrations, assessment of treatment duration. Antimicrobial pharmacokenetic/ pharmacodynamic modelling of pre-clinical and clinical data. Support for clinical trials requiring the above. Help for setting up projects including Point-of-Care Tests involving the above. We serve a wide range of partners and clients, including healthcare institutions, research organizations, and pharmaceutical companies. Whether you require routine susceptibility testing or are engaged in antimicrobial research and development, our services can be tailored to meet your specific needs. Benefits of our Antimicrobial Susceptibility Testing Services: Accurate and Reliable Results: We employ validated methods and strict quality control measures to ensure the accuracy and reliability of our testing. Comprehensive Testing: We offer a full range of standard antimicrobial susceptibility testing methods to assess the susceptibility of microorganisms to various antimicrobial agents. Advanced Hollow-Fibre Infection Model: Our unique expertise in the hollow-fibre infection model allows us to provide in-depth insights into drug efficacy, dosing regimens, and resistance development. Expert Analysis and Interpretation: Our team of scientists provides thorough analysis and interpretation of the results, offering valuable insights and recommendations. Customized Solutions: We understand that each project is unique. We work closely with our clients to tailor our services to their specific requirements, ensuring the most relevant and impactful testing approach.

Contact Us

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Antimicrobial Pharmacokinetic Pharmacodynamic Laboratory UCL Great Ormond Street Institute of Child Health 30 Guilford Street London WC1N 1EH Email: mail@antimicrobialpkpdlab.co.uk hfim@ucl.ac.uk