Pre-Clinical Drug Screening
Comprehensive antimicrobial testing services to support the early stages of antimicrobial drug discovery and development. Our expertise in translational pre-clinical screening enables us to identify and evaluate potential antimicrobial agents with promising activity against microbial pathogens. Using state-of-the-art screening platforms and methodologies, we conduct rigorous and systematic assessments of novel compounds to determine their antimicrobial properties. Our goal is to identify candidates that demonstrate potent activity, selectivity, and a favorable safety profile. With our pre-clinical screening services, we provide valuable data to guide decision-making in the drug discovery process. Our Approach to Pre-clinical Antimicrobial Drug Screening: Minimum Inhibitory Concentration (MIC) Determination: we employ well-established MIC assays to determine the minimum concentration of a compound needed to inhibit the growth of specific pathogens. MIC determination provides valuable information about the potency of compounds and helps in comparing their activities against different microbial strains. Mechanism of Action Studies: In-depth investigations into the mechanism of action of promising compounds help elucidate their antimicrobial activity and provide insights into their potential targets. This knowledge is invaluable for further optimization and understanding the compound's mode of action. Data Analysis and Interpretation: Our experienced scientists provide comprehensive data analysis and interpretation, allowing you to make informed decisions regarding the selection and prioritization of potential antimicrobial candidates for further development. At APPL, we understand the urgency and importance of finding new antimicrobial agents. Our pre-clinical antimicrobial drug screening services provide a solid foundation for your drug discovery efforts, enabling you to identify promising candidates that can potentially address unmet medical needs. Contact us today to discuss how our pre-clinical screening services can support your antimicrobial drug discovery endeavors. Together, we can advance the development of effective therapies and combat the growing challenge of antimicrobial resistance.

Contact Us

---

Antimicrobial Pharmacokinetic Pharmacodynamic Laboratory UCL Great Ormond Street Institute of Child Health 30 Guilford Street London WC1N 1EH Email: mail@antimicrobialpkpdlab.co.uk hfim@ucl.ac.uk