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Antimicrobial Pharmacokinetic/Pharmacodynamic Laboratory

Antimicrobial PKPD Lab Logo

APPL

Antimicrobial PK/PD Laboratory is a pre-clinical antimicrobial testing service facility based at UCL ICH. We are a small dynamic team driven... read more
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Hollow-Fibre Infection Model

The Hollow Fibre Infection Model (HFIM) provides a closed system where organisms can be exposed to... read more
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Antimicrobial Susceptibilty Testing

We specialize in providing comprehensive testing solutions to assess the effectiveness of antimicrobial agents... read more

Our Services


Welcome to our comprehensive suite of services specialising in translational antimicrobial susceptibility testing, antimicrobial pre-clinical drug testing, AMR and pharmacokinetics/pharmacodynamics (PK/PD). We combine traditional microbiological methods with cutting-edge approaches, such as the dynamic hollow-fibre infection model, to deliver accurate and reliable results. We are experts in antimicrobial resistance and our services include: Bacteria Laboratory
  • Hollow-fibre Infection Model

  • Antitmicrobial Susceptibility Testing

  • Pre-clinical Antimicrobial Drug Screening

  • PK/PD


  • Selected Publications

    Replacing Animal Experiments


      Image depicting no mouse experiments We are committed to using, researching and developing alternatives to animal experiments and none of our research has involved animals.

    Animal experimental models are currently viewed as the best predictor of antimicrobial drug efficacy in humans, but they often lack translational power. The UK Government formed the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) to improve animal welfare, reduce experiments where alternatives exist. We are advancing these principles by demonstrating the validity of the hollow-fibre infection model as a viable alternative to early-stage antimicrobial drug testing in animals. read more...


     

    Contact Us


    Antimicrobial Pharmacokinetic Pharmacodynamic Laboratory
    UCL Great Ormond Street Institute of Child Health
    30 Guilford Street
    London WC1N 1EH

    Email:
    mail@antimicrobialpkpdlab.co.uk
    hfim@ucl.ac.uk
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